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Serum or plasma concentration of albumin (qualitative or semi-quantitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal levels of albumin, a protein that helps maintain fluid balance in your body. Low albumin may indicate conditions like malnutrition, kidney disease, or liver problems.

Quick summary

["Albumin levels can signal underlying health issues that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49224-9
Short code
WBC #/area Smn HPF
Synonyms
WBC #/area Smn HPF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-hpf
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order an albumin screening test to monitor conditions affecting protein levels, such as kidney disease, liver disease, or chronic infections. It can also be part of a general health check or during treatment for malnutrition or fluid imbalances.

What does the result mean?

Results are often reported qualitatively (e.g., low, normal, high) rather than with exact numbers. Low albumin may suggest fluid retention, poor nutrition, or organ dysfunction. High levels might indicate dehydration or certain inflammatory conditions.

What affects this test?

Factors like diet (especially protein intake), kidney or liver disease, infections, or medications (e.g., diuretics) can influence albumin levels. Recent blood loss, severe illness, or stress may also impact results temporarily.

How is the test performed?

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab for analysis using a qualitative or semi-quantitative method, such as nephelometry or turbidimetry, to detect protein concentration.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Albumin screening helps identify conditions that may require medical attention. Low albumin is often associated with poor nutritional status, chronic diseases, or fluid shifts. Doctors may use these results to guide treatment for conditions like cirrhosis, kidney failure, or severe infections.

Short name

Albumin screening (serum/plasma)

Frequently asked questions

What does a low albumin result mean?
A low albumin result may indicate conditions like malnutrition, kidney disease, or liver problems. It can also signal fluid retention (e.g., edema) or inflammation. Your doctor will discuss next steps, which may include further tests or dietary/lifestyle changes.
Can diet affect my albumin test results?
Yes, diet plays a role. Low protein intake can lower albumin levels, while certain medical conditions (e.g., kidney or liver disease) may also affect results. Your doctor may recommend dietary adjustments or additional tests if needed.
How often should I get this test?
Frequency depends on your health status. If you have a chronic condition (e.g., kidney or liver disease), your doctor may order this test regularly. Otherwise, it’s often done as part of routine check-ups or when symptoms suggest underlying issues.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy