Skip to content

White Blood Cell Count (Peripheral Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of white blood cells in a sample of your blood. White blood cells help protect your body from infections and diseases.

Quick summary

["Your doctor may order this test to check for infections, immune system issues, or other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49498-9
Short code
WBC # Bld Est
Synonyms
WBC # Bld Est
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
estimate
CPT
85004
SNOMED
900000000000003002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may perform a white blood cell count to diagnose or monitor conditions such as infections (like pneumonia or urinary tract infections), autoimmune diseases (like lupus or rheumatoid arthritis), blood disorders (like leukemia), or to check for signs of inflammation in your body. It can also be used during pregnancy to monitor fetal health or after certain treatments.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your healthcare provider know—they can help make the process more comfortable.

What the Results Mean

The test result shows your total white blood cell count. A higher-than-normal count may indicate an infection, inflammation, or other medical conditions. A lower-than-normal count could suggest immune system problems or blood disorders. Your doctor will interpret the results in the context of your overall health and symptoms.

Common Conditions Monitored

This test is often used to track conditions like chronic infections, cancer (such as leukemia), or immune deficiencies. It may also be checked regularly if you have a history of frequent infections or certain chronic illnesses.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Count

Frequently asked questions

What might cause an elevated white blood cell count?
Elevated white blood cell counts can result from infections (bacterial, viral, or fungal), stress, inflammation, or certain medications. It may also be seen in autoimmune diseases or during pregnancy.
What might cause a decreased white blood cell count?
A low white blood cell count can occur due to infections, certain medications, autoimmune diseases, or conditions affecting bone marrow (like chemotherapy). It may also be linked to nutritional deficiencies or chronic illnesses.
How often should this test be repeated?
Your doctor will determine how often to repeat this test based on your symptoms, medical history, and treatment plan. Follow-up may be needed if you have ongoing health concerns or if your results suggest an underlying issue.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy