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White Blood Cell Clumping (Leukocyte Aggregation) Screening by Automated Fluid Analysis

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal clumping of white blood cells in a blood sample, which may indicate certain immune system conditions or infections.

Quick summary

["Clumping of white blood cells can sometimes signal underlying health concerns that need further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99933-4
Short code
WBC clumps Fld Ql Auto
Synonyms
WBC clumps Fld Ql Auto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like frequent infections, unexplained fevers, or signs of an overactive immune response. It can also be part of routine blood work to monitor conditions like autoimmune diseases or chronic infections.

What to Expect During the Test

You’ll have a small needle inserted into your arm to draw blood. The blood sample is then analyzed automatically to detect any abnormal clumping of white blood cells. The process usually takes a few minutes, and you may feel a brief pinch or discomfort.

How the Results Are Interpreted

Results are typically qualitative (yes/no) or semi-quantitative, indicating whether clumping is present or not. Abnormal findings may prompt further testing or evaluation by your doctor.

Common Reasons for Abnormal Findings

Clumping of white blood cells can occur due to infections, certain medications, or conditions affecting the immune system. It may also be related to laboratory artifacts or specific blood disorders.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Clumping Screen

Frequently asked questions

What does a positive result mean?
A positive result means that the automated test detected abnormal clumping in your white blood cells. This may require further investigation, such as additional blood tests or a consultation with a hematologist or immunologist, to determine the underlying cause.
Can lifestyle changes affect this test?
While lifestyle factors like diet or stress may influence overall health, they typically do not directly affect the detection of white blood cell clumping in this specific test. However, maintaining good health can support your immune system.
How soon will I get my results?
Results from this screening test are usually available within a few hours to a couple of days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy