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White Blood Cell Clumping (Leukocyte Aggregation) Screening Test

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal clumping of white blood cells, which may indicate certain immune system conditions or infections.

Quick summary

["Clumping of white blood cells can signal underlying health concerns that may need further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105102-8
Short code
WBC clumps # Ur
Synonyms
WBC clumps # Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is WBC Clumping?

White blood cells normally move freely through your bloodstream. In some cases, they may clump together, forming larger aggregates. This can happen due to infections, immune disorders, or certain medications. The test helps identify if this clumping is present.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like fever, fatigue, or unexplained infections. It can also be part of routine blood work to monitor immune function or check for conditions like leukemia or autoimmune diseases.

What Does the Result Mean?

If clumping is detected, it doesn’t always mean a specific diagnosis. The result may prompt further testing, such as a complete blood count (CBC) or additional immune system evaluations. Your doctor will interpret the findings in the context of your symptoms and medical history.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is then examined under a microscope to look for abnormal clumping patterns. This is typically done as part of a routine blood test.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Clumping Screening

Frequently asked questions

WBC clumping can be associated with conditions like chronic infections, certain cancers, or immune system disorders. While it doesn’t always indicate a specific illness, it may signal the need for further investigation to understand your health better.
This test is generally a screening tool and may not provide a definitive diagnosis on its own. It often requires additional tests and clinical correlation to determine the underlying cause.
How often should I get this test?
The frequency depends on your symptoms, medical history, and recommendations from your healthcare provider. Some people may need it periodically if they have an ongoing condition affecting their immune system.
Can lifestyle changes affect WBC clumping?
While certain lifestyle factors like stress or poor nutrition may influence overall immune function, they don’t directly cause WBC clumping. However, maintaining good health can support your immune system overall.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy