Autoantibody Profile to Detect and Monitor Autoimmune Conditions (Autoimmune Panel)
This test measures several antibodies that may indicate an autoimmune condition, where your immune system mistakenly attacks healthy tissues. It helps doctors identify potential causes of symptoms like fatigue, joint pain, or unexplained rashes.
["This screening helps pinpoint whether your immune system is producing antibodies linked to autoimmune diseases."]
Key facts at a glance
- LOINC
- 99775-9
- Short code
- WBC # DiafP Auto
- Synonyms
- WBC # DiafP Auto
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.5
- Ref high
- 11
- Critical range
- 2 N/A – 30 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85004
- SNOMED
- 900000000000003002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test includes antibodies such as antinuclear antibodies (ANA), rheumatoid factor (RF), and others that may be elevated in conditions like lupus, rheumatoid arthritis, or other autoimmune disorders. The method used is typically immunoassay (IA), which detects the presence and sometimes concentration of these antibodies in your blood.
Why It’s Ordered
Your doctor may recommend this test if you have symptoms like persistent fatigue, joint swelling, unexplained skin rashes, or other signs of an autoimmune condition. It’s also used to monitor existing autoimmune diseases to track disease activity.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then tested for the presence of these antibodies. This test is usually done on a single blood draw, though some panels may require follow-up tests.
What to Expect Before the Test
No special preparation is needed, but you may want to avoid smoking or consuming alcohol 24 hours before the test. If you’re on certain medications, let your doctor know, as some may affect test results.
Reference range
Adult: 4.5-11.0 x 10^9/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated levels of these antibodies can signal an autoimmune response. While a positive result doesn’t definitively diagnose an autoimmune disease, it may prompt further testing or a change in treatment plan. Some antibodies are more specific to certain conditions, helping narrow down potential diagnoses.
Short name
Autoimmune Antibody Screen
Frequently asked questions
What does a positive result mean?
Can lifestyle changes affect this test?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy