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Whole Blood Disintegrated Cell Count (Leukocyte Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total number of white blood cells in your blood, which helps assess your immune system and detect infections or inflammatory conditions.

Quick summary

["White blood cells are critical for fighting infections and inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
52999-0
Short code
WBC.disintegrated # Bld
Synonyms
WBC.disintegrated # Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

White blood cells (WBCs) are part of your immune system and include different types of cells like neutrophils, lymphocytes, monocytes, eosinophils, and basophils. This test counts the total number of these cells in your blood sample, often used to evaluate immune function, infection risk, or inflammatory processes.

Why Might You Need This Test?

Your healthcare provider may order this test to diagnose or monitor conditions such as infections (e.g., bacterial, viral), autoimmune diseases, blood disorders, or reactions to treatments like chemotherapy.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The blood is then sent to a lab where it is analyzed to count the total number of white blood cells. This process may involve automated blood cell counters or manual microscopic examination.

What Does a Result Mean?

Results are typically reported as a total WBC count (often in thousands of cells per microliter). While specific reference ranges vary by lab, elevated or low counts may signal underlying health concerns that require further evaluation.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated WBC count may indicate an infection, inflammation, or other immune responses. A low WBC count could suggest immune deficiencies, certain medications, or severe illness. Your provider will interpret results in the context of your symptoms and medical history.

Frequently asked questions

What causes a high white blood cell count?
High WBC counts can result from infections (like colds or urinary tract infections), inflammatory diseases, stress, or certain medications. Chronic conditions such as leukemia or autoimmune disorders may also be involved.
Low WBC counts may be due to infections (like HIV or severe viral illnesses), certain medications, bone marrow disorders, or autoimmune diseases. Stress, malnutrition, or chemotherapy can also contribute.
Your provider will determine the frequency based on your health needs, symptoms, or ongoing treatment. Routine blood tests are often part of general check-ups or monitoring chronic conditions.
Can lifestyle changes affect my WBC count?
Yes, lifestyle factors like diet, exercise, sleep, and stress management can influence immune function. Avoiding infections, staying hydrated, and maintaining a balanced diet may support normal WBC levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy