Bromocresol Purple Protein Electrophoresis (Serum/Plasma)

What This Test Measures

Electrophoresis separates blood proteins based on their size and electrical charge. The Bromocresol Purple dye binds to specific protein groups, allowing for visual differentiation of albumin, alpha, beta, and gamma globulins. This helps evaluate the overall protein profile in your serum or plasma.

How the Test Works

A small blood sample is drawn and placed in a gel medium. An electric current is applied, causing proteins to migrate toward the positive electrode. The dye highlights different protein bands, which are then analyzed for concentration and distribution.

Why It’s Done

This test is often used to diagnose or monitor conditions like chronic inflammation, autoimmune diseases, liver or kidney disorders, or certain types of anemia. It may also be part of a broader evaluation for unexplained symptoms or suspected protein abnormalities.

Common Uses and Conditions

Protein electrophoresis with Bromocresol Purple is particularly useful for detecting abnormal protein patterns, such as those seen in multiple myeloma, Waldenström macroglobulinemia, or other monoclonal gammopathies. It can also help assess albumin levels and globulin fractions in conditions affecting protein synthesis or breakdown.