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White Blood Cell Differential with Automated Counting (Other Blood Components)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells in your blood, excluding the total white blood cell count. It helps identify infections, immune responses, or other blood disorders.

Quick summary

["Understanding your white blood cell types can reveal clues about your health status or underlying conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15190-2
Short code
WBC Other Bld Auto
Synonyms
WBC Other Bld Auto
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85004
SNOMED
900000000000003002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions like infections (bacterial or viral), autoimmune diseases, blood disorders, or reactions to medications. It can also help assess immune function or check for signs of inflammation.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

The test provides percentages of different white blood cell types, such as neutrophils, lymphocytes, monocytes, eosinophils, and basophils. Abnormal levels may indicate infections, allergies, or other health concerns.

Common Conditions Linked to Abnormal Results

High or low counts of specific white blood cells can signal conditions like chronic infections, leukemia, or immune deficiencies. For example, low lymphocytes might suggest HIV or other immune disorders, while high eosinophils could indicate allergies or parasitic infections.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Differential (Auto)

Frequently asked questions

What does an abnormal white blood cell differential usually indicate?
An abnormal differential may suggest infections (e.g., high neutrophils), immune disorders (e.g., low lymphocytes), or inflammatory conditions (e.g., high monocytes). Always discuss results with your healthcare provider.
Can diet or medications affect white blood cell counts?
Certain foods, supplements, or medications (like steroids) can influence white blood cell levels. If you’re unsure, share your full medication list and dietary habits with your doctor.
How often should I get this test?
Frequency depends on your health needs. Your doctor will determine if regular monitoring is necessary, especially if you have chronic conditions like cancer or autoimmune diseases.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy