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White Blood Cell Differential with Other Granulocyte Fractions (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific types of white blood cells (WBCs) in your blood, including non-neutrophil granulocytes, which help identify imbalances that may signal infections, inflammation, or other conditions.

Quick summary

["This test helps doctors understand which types of white blood cells are present beyond just the total count."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26471-3
Short code
WBC Other NFr Bld
Synonyms
WBC Other NFr Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions like chronic infections, autoimmune diseases, or certain cancers. It can also help assess how your body is responding to treatments or infections beyond what a standard WBC count alone shows.

What to Expect Before the Test

You’ll typically have a simple blood draw from a vein, usually in your arm. No special preparation is needed, but avoid strenuous activity 24 hours before the test if possible.

What the Results Mean

Results show the proportions of different WBC types, including eosinophils, basophils, and other granulocytes. Abnormal levels may indicate conditions like allergies, infections, or blood disorders.

Common Conditions Monitored

This test helps track conditions such as chronic granulomatous diseases, certain leukemias, or reactions to medications that affect white blood cells.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Differential (Other Granulocytes)

Frequently asked questions

What does ‘other granulocyte fractions’ include?
‘Other granulocyte fractions’ in this test refers to non-neutrophil WBCs like eosinophils and basophils, which are part of the immune system but not counted in a standard total WBC differential.
How often should I get this test?
Your doctor will determine the frequency based on your health condition, treatment plan, or symptoms. Regular monitoring may be needed if you have chronic illnesses like autoimmune disorders or cancer.
Can diet affect my WBC differential results?
Dietary changes alone won’t drastically alter this test, but certain foods or supplements (e.g., high vitamin C, probiotics) might influence immune cell activity indirectly. Follow your doctor’s advice for any dietary restrictions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy