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Bromocresol Purple Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in your blood using a technique called electrophoresis with the dye bromocresol purple. It helps identify patterns of protein separation that may indicate conditions affecting protein levels or composition.

Quick summary

["This test helps diagnose or monitor conditions related to abnormal protein levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14811-4
Short code
WBC # Pcar Manual
Synonyms
WBC # Pcar Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on size and charge. Bromocresol purple binds to proteins, allowing for visual differentiation of fractions such as albumin, alpha-globulins, beta-globulins, and immunoglobulins. This process helps detect shifts in protein distribution that could signal underlying health issues.

Common Uses

This test is often used to evaluate conditions like multiple myeloma, amyloidosis, chronic liver disease, or other disorders that alter protein synthesis or breakdown. It may also assist in monitoring treatment progress for these conditions.

How the Test Works

A small blood sample is drawn and placed in a gel or medium. An electric current is applied, causing proteins to migrate toward the opposite charge. The bromocresol purple dye stains the proteins, creating visible bands that represent different protein groups.

Sample Collection

Your blood will be drawn from a vein, typically in your arm. This is a standard venipuncture procedure. You may feel a slight pinch, but the process is quick and usually not painful.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCP Protein Electrophoresis

Frequently asked questions

Why might I need this test?
Your doctor may recommend this test if they suspect conditions affecting protein balance, such as liver disease, kidney disease, or certain cancers. It may also be part of routine monitoring for patients with known protein-related disorders.
What does the test result mean?
Results are interpreted by a healthcare professional based on your specific situation. Patterns may show normal protein distribution, or they may reveal shifts that need further investigation, such as additional blood tests or imaging.
How long will it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times and your healthcare provider’s workflow.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy