White Blood Cell Differential with Autoimmune Component Analysis
This test measures the types of white blood cells in your blood and assesses certain immune-related components, often used to evaluate immune function or autoimmune conditions.
["Understanding your immune cell balance and potential autoimmune activity can help guide treatment for infections or inflammatory diseases."]
Key facts at a glance
- LOINC
- 807-8
- Short code
- WBC # Plr Auto
- Synonyms
- WBC # Plr Auto
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 4.5
- Ref high
- 11
- Critical range
- 2 N/A – 30 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85004
- SNOMED
- 900000000000003002
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test evaluates the proportions of different white blood cell types, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. It also includes an automated analysis for markers that may indicate autoimmune activity, such as certain autoantibodies or immune system responses.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like frequent infections, unexplained fatigue, joint pain, or if you’re being evaluated for autoimmune diseases (e.g., lupus, rheumatoid arthritis). It helps determine if your immune system is functioning normally or if there’s an overactive or misdirected response.
How Is the Test Performed?
A small blood sample is drawn from a vein in your arm. The blood is then analyzed in a lab using automated technology to count and classify white blood cells and assess immune-related markers.
What Are Common Results and Next Steps?
Abnormal results may show an imbalance in white blood cell types (e.g., too many or too few neutrophils) or signs of an autoimmune response. Your doctor will discuss these findings with you and may recommend further testing or treatments based on your symptoms and medical history.
Reference range
Adult: 4.5-11.0 x 10^9/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
WBC Differential (Autoimmune Screen)
Frequently asked questions
What does an abnormal white blood cell differential mean for me?
How often should I get this test?
Can lifestyle changes affect my white blood cell counts?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy