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White Blood Cell Differential with Manual Count (Prostate-Specific Fluid)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells in fluid collected from the prostate, which may help assess inflammation or infection in the prostate gland or surrounding tissues.

Quick summary

["Understanding your white blood cell count in prostate fluid can help diagnose or monitor prostate-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72348-6
Short code
WBC # Prost fld Manual
Synonyms
WBC # Prost fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like pain, swelling, or abnormal discharge from the penis, or if you’re experiencing persistent urinary issues. It can also be part of a broader evaluation for conditions like prostatitis (inflammation of the prostate) or prostate cancer screening in certain contexts.

What to Expect Before the Test

You’ll likely undergo a procedure called a **prostate massage** (or manual prostate examination) to collect fluid. This may cause mild discomfort but is generally quick. Avoid ejaculation or sexual activity for 24 hours before the test to ensure accurate results.

What the Test Results Mean

The test looks at different types of white blood cells (neutrophils, lymphocytes, etc.) in the fluid. Elevated counts of certain cells may indicate infection, inflammation, or other prostate-related issues. Results are interpreted by your healthcare provider based on your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test can help identify conditions such as prostatitis (inflammation of the prostate), bacterial infections, or even early signs of prostate cancer in some cases. It’s not a standalone test but often used alongside other diagnostic tools.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: When This Test Matters

Short name

WBC Differential in Prostate Fluid

Frequently asked questions

When might I need this test?
Your doctor may recommend this test if you have symptoms like persistent urinary issues, pain during urination, or unexplained swelling near the prostate. It’s also sometimes used in research or specialized diagnostic settings for prostate-related concerns.
What does a high or low white blood cell count in this fluid mean?
A high count of certain white blood cells (like neutrophils) often suggests infection or inflammation. A low count might indicate a lack of immune response in the prostate fluid, though this is less common. Always discuss results with your provider—they’ll consider your full medical picture.
Can I take medications before this test?
Avoid antibiotics or anti-inflammatory medications for at least 24 hours before the test, as they may affect the results. Follow your doctor’s specific instructions, as some medications (like those for prostate health) may need to be adjusted.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy