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White Blood Cell Differential (with Percentage)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells in your blood, helping identify infections, inflammation, or other immune system issues.

Quick summary

["Understanding your white blood cell types can help pinpoint health concerns like infections or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26468-9
Short code
WBC # Prt
Synonyms
WBC # Prt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test breaks down white blood cells into categories such as neutrophils, lymphocytes, monocytes, eosinophils, and basophils, along with their relative percentages. This helps assess immune function and response to illness.

Why Might You Need This Test?

Doctors may order this test to diagnose or monitor conditions like infections (e.g., bacterial or viral), autoimmune diseases, or blood disorders. It’s also used during cancer treatment to check for side effects or monitor recovery.

How Is the Sample Collected?

A small blood sample is taken from a vein, usually in your arm. The blood is then analyzed in a lab to determine the types and percentages of white blood cells.

What Are Common Results?

Results show the absolute counts and percentages of each white blood cell type. Abnormal percentages or counts may signal underlying health issues that need further evaluation.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal WBC differentials can indicate infections (e.g., high neutrophils for bacterial infections, high lymphocytes for viral infections), chronic conditions (e.g., leukemia or lymphoma), or inflammatory diseases. Low counts of certain cells may suggest immune deficiencies or other systemic problems. Always discuss results with your healthcare provider for personalized insights.

Short name

WBC Differential %

Frequently asked questions

What Does an Abnormal Test Mean?
An abnormal result doesn’t necessarily mean you have a serious condition, but it may prompt further testing. Your doctor will consider your symptoms, medical history, and other test results to determine the next steps.
How Often Should I Get This Test?
Frequency depends on your health needs. Some people get it regularly during treatment for chronic illnesses, while others may need it only if symptoms arise or during routine check-ups.
Can Lifestyle or Diet Affect This Test?
While diet and lifestyle factors like stress or recent illness can temporarily influence white blood cell counts, they don’t usually alter the differential percentages. Avoid extreme diets or supplements before testing unless advised by your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy