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White Blood Cell Differential with Microbial Identification (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test examines the types of white blood cells in your blood and checks for signs of infections or other immune system responses.

Quick summary

["It helps identify infections, inflammation, or immune disorders by analyzing your blood cells and potential microbes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13655-6
Short code
WBC Stl Ql Micro
Synonyms
WBC Stl Ql Micro
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What This Test Measures

The test first looks at the proportions of different white blood cell types (neutrophils, lymphocytes, monocytes, eosinophils, basophils) to assess immune function and possible infections. The second part involves screening for microbial presence, such as bacteria or fungi, using a qualitative method that detects their genetic material or specific markers.

Why It Matters in Your Health

A differential white blood cell count helps doctors diagnose conditions like infections, autoimmune diseases, or blood disorders. Microbial screening supports identifying infections that may require antibiotics or other treatments.

Common Reasons for This Test

You may need this test if you have symptoms like fever, persistent fatigue, unexplained weight loss, or signs of infection (e.g., sore throat, skin rashes). Doctors also use it to monitor chronic conditions like leukemia, lupus, or immune deficiencies.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours if blood is drawn for the differential alone. Bring any medications or recent illnesses to discuss with your provider.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: stool

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Differential + Microbe Screen

Frequently asked questions

How does the test help my doctor diagnose my condition?
The differential helps determine if your symptoms are due to bacterial, viral, or other infections by showing shifts in white blood cell counts. Microbial screening confirms if a pathogen is present, guiding treatment decisions like antibiotics or antifungal drugs.
Can this test detect all types of infections?
This test screens for common microbial markers but may not detect all infections. Additional tests (e.g., cultures, PCR) may be needed for specific pathogens or severe cases.
What if my results show abnormal white blood cells?
Abnormal counts may indicate infections, inflammation, or blood disorders. Your doctor will review results with you and may recommend further testing or treatments based on your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy