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White Blood Cell Differential with Quantitative Microbial Count (if applicable)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells in your blood and checks for potential microbial presence, such as bacteria or fungi.

Quick summary

["It helps diagnose infections, immune disorders, and other blood-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107472-3
Short code
WBC Tiss Ql Micro
Synonyms
WBC Tiss Ql Micro
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does the Test Measure?

The test evaluates five main types of white blood cells (neutrophils, lymphocytes, monocytes, eosinophils, and basophils) by examining their proportions in your blood. If the slug includes 'micro,' it may also assess microbial indicators (e.g., bacterial or fungal load) using advanced methods like culture or molecular testing.

Why Might You Need This Test?

Your doctor may order this test to identify infections (such as bacterial or fungal), evaluate immune system function, check for blood disorders (like leukemia or anemia), or monitor conditions like chronic inflammation.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The sample is processed to count and identify white blood cell types. If microbial screening is included, additional testing (e.g., culture or PCR) may be done on the sample to detect pathogens.

What Are Common Results and Next Steps?

Abnormal proportions of white blood cells can signal infections, allergies, or immune issues. Elevated or low counts may prompt further testing, such as blood cultures or additional immune function tests. Microbial results may indicate infection requiring antibiotics or antifungal treatment.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Differential + Microbial Screening

Frequently asked questions

What Are My Test Results Meaning?
Your results will be reviewed by a healthcare provider who will compare them to your symptoms and medical history. For example, a high neutrophil count might suggest infection, while a low lymphocyte count could indicate immune suppression. If microbial screening is included, positive results may lead to targeted treatment for infections.
How Often Should I Get This Test?
Frequency depends on your health condition. Routine blood tests (like a complete blood count) may include this differential, while specific conditions (e.g., chronic infections, cancer) may require more frequent monitoring.
Can I Prepare for This Test?
No special preparation is needed, but avoid heavy meals or strenuous activity 12 hours before the blood draw. If you’re on medications, let your doctor know to ensure they’re accounted for in results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy