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White Blood Cell Differential with Autoimmune Inflammatory Factor Screening (Autoimmune White Blood Cell Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain types of white blood cells and evaluates potential markers related to autoimmune or inflammatory conditions in your blood.

Quick summary

["Helps identify immune system activity and possible underlying inflammatory or autoimmune processes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68434-0
Short code
WBC # Vitf Auto
Synonyms
WBC # Vitf Auto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes a differential count of white blood cells (neutrophils, lymphocytes, monocytes, eosinophils, basophils) and assesses specific markers (vitamin-related or metabolic factors) that may indicate autoimmune activity or inflammation. Some tests may also evaluate cell function or activity levels indirectly.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, unexplained fever, joint pain, or signs of an overactive immune system. It could also be used to monitor conditions such as autoimmune diseases, chronic inflammation, or immune-related side effects from treatments.

Common Conditions Monitored

This profile helps track conditions like rheumatoid arthritis, lupus, inflammatory bowel disease, or other autoimmune disorders. It may also assist in evaluating immune system responses to infections or medications.

What to Expect Before the Test

No special preparation is typically needed. You may have a simple blood draw, and results will be reviewed by your healthcare team.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC Autoimmune Profile

Frequently asked questions

What does an abnormal result mean?
An abnormal result doesn’t always mean you have a specific condition, but it may prompt further testing or discussions with your doctor to explore possible causes.
How often should I get this test?
Your doctor will determine the frequency based on your health needs, symptoms, and treatment plan. Regular monitoring may be needed if you have an ongoing condition.
Can lifestyle changes affect these test results?
Yes, diet, stress levels, and certain medications can influence immune activity. Discuss any changes with your healthcare provider to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy