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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110777-0
Short code
WEEV IgM Msmt Ser
Synonyms
WEEV IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like muscle weakness, nerve problems, or if you have conditions that affect fat absorption (e.g., celiac disease, Crohn’s disease). It may also be part of a routine check for vitamin deficiencies or certain genetic disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s a blood draw, but confirm with your lab. Avoid taking vitamin E supplements for a few days before testing if instructed.

How the Test Is Performed

A blood sample is taken from a vein in your arm. The blood is then processed to separate serum or plasma for analysis. The test measures the concentration of alpha-tocopherol (vitamin E) using a sensitive laboratory method.

Possible Results and Interpretation

Results are compared to reference ranges specific to your lab. Low levels may suggest malabsorption, certain medical conditions, or poor dietary intake, while very high levels could indicate excessive supplementation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin E level

Frequently asked questions

What does a low vitamin E level mean?
Low vitamin E levels may indicate underlying health issues like liver disease, cystic fibrosis, or malabsorption syndromes. It can also be linked to certain genetic disorders or prolonged use of certain medications. Your doctor will review your symptoms and other test results to determine the cause.
What does a high vitamin E level mean?
Elevated vitamin E levels are less common but may occur with long-term vitamin E supplementation. Rarely, it can be associated with certain genetic disorders or liver conditions. Your doctor will discuss your results in the context of your overall health.
How often should I get this test?
The frequency depends on your health status. If you have a known condition affecting vitamin E absorption, your doctor may recommend regular monitoring. Otherwise, this test is often done as part of a broader nutritional assessment or when symptoms suggest a deficiency.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy