Candida albicans antigen in serum/plasma (quantitative)

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like fever, chills, or unexplained infections, especially if you’ve recently been treated with antibiotics or have conditions like HIV/AIDS, diabetes, or cancer. It’s also used to monitor people at higher risk of invasive candidiasis (a serious yeast infection spreading beyond the skin or mouth).

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The test involves a few drops of blood, and it usually takes less than 10 minutes. If you’re on blood thinners, let your provider know before the test.

What the Test Measures

This test measures specific proteins (antigens) produced by Candida albicans in your blood. These antigens are not naturally found in healthy people, so they indicate an active infection. The test helps confirm whether the yeast is spreading beyond the mouth or skin into deeper tissues.

Possible Results and Next Steps

A positive result means your blood contains Candida antigens, suggesting an infection. A negative result means no detectable antigens were found, but this doesn’t always rule out infection—other tests or samples may be needed. Your provider will discuss next steps, such as further testing or treatment options.