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Serum or Plasma Bromocresol Green Protein Binding Test

Published: August 9, 2026Updated: August 17, 2026

This test measures how bromocresol green dye binds to proteins in your blood, often used to assess liver function and protein synthesis.

Quick summary

["A key indicator of liver health and protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102927-1
Short code
Wheat Bran IgG4 RAST
Synonyms
Wheat Bran IgG4 RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates the protein-binding capacity of serum or plasma using bromocresol green dye. When the dye binds to proteins, it changes color, allowing for measurement of protein levels indirectly. This reflects how well your liver produces and maintains proteins like albumin.

Why It Matters in Medicine

Protein binding by bromocresol green is primarily used to assess liver function, particularly the synthesis of plasma proteins. Abnormal results may suggest liver disease, malnutrition, or other conditions affecting protein metabolism.

Common Uses and Indications

Doctors may order this test to diagnose or monitor liver conditions, such as cirrhosis or hepatitis, or to evaluate nutritional status in patients with chronic illnesses.

Sample Collection and Preparation

Blood is drawn from a vein, typically in the arm. The sample is processed to separate serum or plasma, which is then analyzed for protein binding capacity.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Protein Binding

Frequently asked questions

How might my results affect my treatment plan?
Results may guide decisions about liver function management, protein supplementation, or further diagnostic testing if protein abnormalities are detected.
What does a low or high result mean?
Low results may indicate liver disease, malnutrition, or severe protein loss, while high results could suggest dehydration or certain liver conditions. Your doctor will interpret results in the context of your overall health.
Is this test painful?
Blood draws are generally mild discomfort, but most patients tolerate it well. The procedure takes a few minutes, and you may feel a slight pinch when the needle is inserted.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy