Serum or plasma mass concentration of total protein

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of health issues, such as dehydration, liver or kidney disease, malnutrition, or certain immune disorders. It can also help diagnose conditions like nephrotic syndrome or protein-losing gastrointestinal diseases.

What to Expect Before the Test

No special preparation is usually needed. If you’re having blood drawn, you may experience a brief pinch or slight discomfort. Avoid eating or drinking for 8–12 hours before the test if instructed, as it may affect results.

What the Results Mean

Results are compared to a general reference range, but individual values can vary based on age, health, and other factors. Low protein levels may indicate fluid loss or organ dysfunction, while very high levels could suggest conditions like multiple myeloma or severe dehydration.

Common Conditions Linked to Protein Levels

Abnormal protein levels can signal underlying health concerns. For example, low protein might point to liver disease, kidney failure, or severe infections, while high protein could signal conditions like dehydration, inflammation, or certain cancers.