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Total Protein with Albumin-to-Globulin Ratio (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood’s total protein levels and evaluates the balance between albumin and globulin proteins, which can help assess nutritional status and immune function.

Quick summary

["Your blood’s protein balance may signal nutritional deficiencies or immune issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51008-1
Short code
Wheat (nTri a) 19 IgE Qn
Synonyms
Wheat (nTri a) 19 IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Measured?

Total protein includes albumin and globulin proteins, which are vital for transporting nutrients, maintaining fluid balance, and supporting immune responses. The albumin-to-globulin (A/G) ratio compares these two protein types.

Why Is This Test Done?

Doctors may order this test to check for malnutrition, liver disease, chronic infections, or other conditions affecting protein production or balance.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The serum (liquid part after clotting) is then analyzed in a lab.

What Are Common Results?

Results may show elevated or low protein levels, or an abnormal A/G ratio, depending on underlying health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein + A/G Ratio

Frequently asked questions

What does a high or low total protein mean?
A high total protein could suggest dehydration, chronic inflammation, or certain cancers. A low total protein may point to malnutrition, liver or kidney problems, or severe infections.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can diet affect these test results?
Yes, high-protein diets or certain medical conditions (like kidney disease) may influence protein levels. Follow-up with your doctor if you have concerns about diet or test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy