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Total White Blood Cell Count (Serum/plasma Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of white blood cells in a blood sample. White blood cells help your body fight infections and diseases.

Quick summary

["A WBC count helps doctors assess your immune system health and detect infections or other conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61286-1
Short code
White mulberry IgE/IgE total %
Synonyms
White mulberry IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Done

Doctors may order a white blood cell count to check for signs of infection, inflammation, immune disorders, or other health issues. It’s often part of routine blood tests or used to monitor conditions like leukemia, autoimmune diseases, or chronic illnesses.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn from a vein, but this depends on your doctor’s instructions. Avoid strenuous activity or medications that could affect results.

How the Test Works

A small blood sample is taken from a vein in your arm. The sample is sent to a lab where machines analyze the different types of white blood cells. The test measures the total count of these cells, not their individual types.

What the Results Mean

Results are typically reported as a total count (often in thousands of cells per microliter). High or low counts can signal underlying health concerns, but your doctor will interpret results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated white blood cell counts may indicate infections, stress, inflammation, or certain cancers. Low counts can suggest immune deficiencies, bone marrow disorders, or severe infections. Your doctor will use these results alongside other tests to guide diagnosis and treatment.

Short name

WBC Total

Frequently asked questions

What causes a high white blood cell count?
High WBC counts can be caused by infections (like bacterial or viral), chronic illnesses (such as rheumatoid arthritis), stress, or certain medications. It may also appear during recovery from surgery or illness.
What causes a low white blood cell count?
Low WBC counts can result from infections, autoimmune diseases, chemotherapy, or conditions affecting bone marrow production. Rarely, it may be genetic or linked to long-term medications.
Do I need to do anything special after the test?
No special follow-up is needed unless your doctor advises it. If you experience bruising or discomfort at the injection site, apply ice or rest the arm. Report any unusual symptoms (fever, fatigue) to your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy