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Total Egg IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of Immunoglobulin E (IgE), a type of antibody linked to allergic reactions and certain immune responses.

Quick summary

["IgE levels help identify allergies or immune system sensitivities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41288-2
Short code
Whole Egg IgE/IgE total %
Synonyms
Whole Egg IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to diagnose allergies (e.g., to foods, pollen, or pets), evaluate chronic inflammatory conditions, or assess immune function in certain diseases. It can also help monitor treatment responses in patients with known IgE-related conditions.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The blood is processed to separate serum, which is then analyzed for IgE levels using an immunoassay method.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications you’re taking, as some may affect results. Avoid alcohol for 24 hours before testing if instructed.

What Are Common Results?

Results are typically reported in arbitrary units per milliliter (U/mL). Elevated IgE levels may suggest allergies, asthma, or other allergic disorders, while normal or low levels may indicate no active allergic response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High IgE levels often point to allergic reactions, such as hay fever, food allergies, or atopic dermatitis. They may also be associated with parasitic infections or certain autoimmune conditions. Low IgE levels can sometimes indicate a weakened immune response to allergens or other underlying immune deficiencies.

Short name

Total IgE (Serum)

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels can result from allergies (e.g., to environmental triggers, foods, or medications), chronic inflammatory diseases (e.g., asthma, eczema), or parasitic infections. Genetic factors may also play a role in predisposing someone to high IgE.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, immune responses, or underlying health conditions. Treatment for allergies (e.g., medications, immunotherapy) may lead to temporary or permanent reductions in IgE levels.
Is there anything I should avoid before this test?
Avoid excessive alcohol consumption for 24 hours before the test, as it may affect blood test results. If you’re on medications that suppress the immune system (e.g., steroids), let your doctor know to ensure accurate interpretation of results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy