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Kidney Function: Urine Albumin-to-Creatinine Ratio (24-hour collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of albumin (a protein) and creatinine (a waste product from muscles) in your urine over 24 hours. It helps assess how well your kidneys are filtering blood and detecting early signs of kidney damage.

Quick summary

["A 24-hour urine test for albumin-to-creatinine ratio helps track kidney health and early kidney disease risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15287-6
Short code
Width Kidney-L US.meas
Synonyms
Width Kidney-L US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Kidney Health

Kidneys filter waste and excess substances from your blood, including proteins like albumin. High albumin levels in urine can signal kidney damage or conditions like diabetes or high blood pressure. This test is especially useful for monitoring kidney function in people with risk factors for kidney disease.

How the Test Works

You’ll collect all your urine for 24 hours in a special container. The lab measures the ratio of albumin to creatinine in your urine sample. This ratio helps doctors determine if your kidneys are working properly or if protein is leaking into your urine.

What to Expect Before the Test

No special preparation is needed, but you’ll need to collect every drop of urine for 24 hours. Drink enough fluids to produce urine throughout the day, but avoid excessive alcohol or caffeine, which may affect results.

What to Expect During the Test

You’ll return the 24-hour urine sample to your lab or clinic. The lab will process it to measure albumin and creatinine levels, then calculate the ratio. Results are typically ready within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated albumin in urine (microalbuminuria) can indicate early kidney damage, often linked to diabetes or hypertension. A normal ratio suggests healthy kidney function, while higher ratios may signal kidney strain. Regular monitoring with this test helps manage kidney health and prevent progression of kidney disease.

Short name

Albumin:Creatinine Ratio (Urine, 24h)

Frequently asked questions

What does a high or low ratio mean?
A high albumin-to-creatinine ratio may mean your kidneys are not filtering proteins properly, which can happen with diabetes, high blood pressure, or other kidney-related conditions. A low ratio usually indicates normal kidney function, but your doctor may still recommend follow-up testing if you have risk factors.
Does diet affect this test?
Diet can influence urine volume and protein levels. Avoid high-protein diets or excessive salt for a few days before testing, as they may affect results. Stick to a normal diet during the 24-hour collection period.
How often should I get this test?
Your doctor may recommend this test periodically if you have diabetes, high blood pressure, or a family history of kidney disease. Follow your healthcare provider’s schedule for retesting to monitor kidney health over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy