Prostate-Specific Antigen (PSA) Mass Concentration in Serum

Why Is This Test Done?

Doctors may order PSA testing to monitor prostate health, especially if you have symptoms like frequent urination, difficulty urinating, blood in urine, or pain in the pelvic area. It’s also used during screenings for prostate cancer, especially in men at higher risk. PSA levels can help track changes over time if you’ve already been diagnosed with prostate issues.

What Does a PSA Test Involve?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure PSA levels. You may need to fast for a few hours before the test, but this isn’t always required.

How Is the PSA Test Performed?

The blood is processed to separate serum (the liquid part) for analysis. The PSA protein in the serum is measured using a sensitive lab technique, often an immunoassay, to detect and quantify it accurately.

What Do PSA Results Mean?

PSA results alone don’t diagnose prostate cancer—they’re part of a broader evaluation. Higher-than-normal levels can signal prostate issues, but other factors like age, race, and medical history also play a role. Your doctor will discuss results in the context of your overall health.