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Lipid Profile: Total Cholesterol (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which includes both HDL (good) and LDL (bad) cholesterol. Cholesterol is a fat-like substance that your body needs for healthy cells but can become harmful if levels are too high.

Quick summary

["Your cholesterol levels help assess your risk for heart disease and other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15293-4
Short code
Width Testis-L US.meas
Synonyms
Width Testis-L US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Cholesterol is an essential component of cell membranes and a precursor to hormones and vitamin D. However, having too much cholesterol in your blood can lead to plaque buildup in your arteries, increasing the risk of heart disease or stroke. This test helps doctors monitor your overall cardiovascular health and guide treatment if needed.

What to Expect Before the Test

No special preparation is required for this test. You may have a small needle inserted into your arm to draw a blood sample. If you’re fasting, your doctor will advise you to avoid eating or drinking (except water) for 12 hours before the test. Fasting may be recommended if your doctor suspects high cholesterol.

What the Results Mean

Your cholesterol results will show your total cholesterol level, which is the sum of HDL, LDL, and triglycerides. While exact reference ranges vary by lab, higher-than-normal levels may indicate a need for lifestyle changes, diet adjustments, or medication to manage your health.

Common Causes and Risk Factors

High cholesterol can be influenced by genetics, diet (e.g., high intake of saturated or trans fats), lack of physical activity, obesity, smoking, or certain medical conditions like diabetes or high blood pressure. Some medications may also affect cholesterol levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cholesterol plays a critical role in maintaining normal bodily functions, but consistently high levels can damage blood vessels over time. Regular monitoring helps prevent serious complications like heart attacks or strokes. If your results are concerning, your doctor may recommend further testing or treatments.

Short name

Total Cholesterol

Frequently asked questions

What does a high cholesterol level mean for my health?
A high cholesterol level may increase your risk of heart disease or stroke by promoting plaque buildup in your arteries. Your doctor will discuss your results in detail and may suggest lifestyle changes or medications to help lower your cholesterol.
How can I lower my cholesterol naturally?
Eating a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, reducing saturated and trans fats, and exercising regularly can help improve cholesterol levels. Avoiding smoking and maintaining a healthy weight also play important roles.
Do I need to fast before this test?
Yes, fasting for 12 hours before the test (eating or drinking except water) may be required, especially if your doctor suspects high cholesterol. Always follow your healthcare provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy