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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to certain substances.

Quick summary

["IgE helps identify allergies or immune responses that may affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61310-9
Short code
Willow IgE/IgE total %
Synonyms
Willow IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens (substances like pollen, dust, or certain foods) or other triggers. While IgE is normal in small amounts, higher levels may suggest allergies, asthma, or other immune-related conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, rashes, or breathing difficulties that suggest allergies. It can also help diagnose conditions like hay fever, eczema, or certain types of asthma.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab where it is analyzed to measure IgE levels using immunoassay techniques.

What Do Results Mean?

Results are not given as a single reference range since IgE levels vary widely depending on age, health, and exposure. High IgE levels may indicate allergies or immune disorders, while normal or low levels may suggest no active allergic response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Blood Test

Frequently asked questions

How often should I expect this test?
This test is typically ordered as needed, often when symptoms of allergies or suspected immune issues arise. Your doctor may recommend follow-up testing if results are abnormal or if symptoms persist.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, immune responses, or underlying health conditions. Repeated testing may be required to monitor changes.
What if my IgE levels are high?
High IgE levels often point to allergies or allergic conditions. Your doctor may recommend allergy testing, treatment plans (like antihistamines or allergy shots), or further evaluation to address the underlying cause.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy