Macromolecular Protein Electrophoresis (Serum/Plasma)

What This Test Measures

Electrophoresis separates blood proteins based on size and charge, allowing for visual inspection of bands corresponding to various protein types. This method helps detect unusual protein levels or patterns that may not be visible in standard blood tests.

Common Uses

Doctors may order this test to diagnose or monitor conditions like multiple myeloma (a cancer of plasma cells), amyloidosis (a buildup of abnormal proteins in organs), or kidney disease (e.g., nephrotic syndrome). It can also help evaluate protein abnormalities in chronic inflammatory diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is then processed to separate serum or plasma for analysis. This test does not require fasting but may be performed on a specific day of the week for consistency.

How Results Are Interpreted

Results are presented as a visual pattern of protein bands. Abnormal bands or shifts may indicate specific protein disorders. Your healthcare provider will compare these findings to your medical history and other test results to determine next steps.