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Serum or Plasma Immunoassay for Homovanillic Acid (HVA)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of homovanillic acid (HVA) in your blood or plasma. HVA is a breakdown product of dopamine, a neurotransmitter involved in mood regulation and movement.

Quick summary

["HVA helps assess dopamine metabolism, which may be important in conditions like Parkinson’s disease or certain mood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7781-8
Short code
Wormwood IgG Qn
Synonyms
Wormwood IgG Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HVA Used For?

Doctors may order this test to evaluate dopamine function in cases of suspected neurological disorders, such as Parkinson’s disease, or to monitor treatment responses in patients with conditions affecting dopamine levels. It can also be part of broader metabolic or neurochemical assessments.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then processed into either serum (after clotting) or plasma (using an anticoagulant). The HVA level is measured using an immunoassay method, which detects specific chemical markers in the sample.

Preparation and Timing

No special preparation is typically needed for this test. However, your doctor may advise avoiding certain medications or foods that could influence dopamine metabolism before the test. Results may take several days to weeks to process, depending on lab capacity.

What Are Possible Results?

Results are presented as a concentration value (e.g., micrograms per liter) but do not include specific reference ranges. Interpretation depends on clinical context, such as whether the test is part of a diagnostic evaluation or monitoring plan.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HVA Level

Frequently asked questions

Why might my doctor request this test?
Your doctor may order this test if they suspect a neurological disorder affecting dopamine, such as Parkinson’s disease, or if you are undergoing treatment for conditions like depression, ADHD, or other mood-related disorders. It may also be part of research studies or specialized metabolic evaluations.
What do my HVA results mean for my health?
HVA results alone do not diagnose a condition. They are used alongside other tests, symptoms, and medical history to guide further evaluation. Your doctor will explain how these results fit into your overall care plan.
Can lifestyle or diet affect HVA levels?
Certain foods, medications, or supplements (e.g., tyrosine, dopamine precursors) may influence dopamine metabolism and indirectly affect HVA levels. Always inform your doctor about all medications or dietary changes before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy