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Serum/plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein status and kidney function.

Quick summary

["Your blood protein levels can indicate hydration, kidney health, or nutritional needs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55341-2
Short code
Xg sup(a) Ab Titr SerPl
Synonyms
Xg sup(a) Ab Titr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for conditions like dehydration, kidney disease, liver problems, or malnutrition. It can also help monitor protein loss due to conditions like kidney failure or certain cancers.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Higher than expected levels might suggest dehydration, multiple myeloma, or severe liver disease. Lower levels could indicate kidney disease, malnutrition, or severe burns.

Common Conditions Affecting Results

Conditions like kidney disease, liver disease, or severe infections can change protein levels. Hormonal changes, pregnancy, or certain medications may also impact results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein (Serum/Plasma)

Frequently asked questions

What causes my protein levels to be unusually high?
High protein levels can result from dehydration, certain cancers (like multiple myeloma), or severe liver disease. If you notice unexplained weight loss, fatigue, or swelling, discuss these results with your doctor.
How often should I get this test?
Your doctor will determine frequency based on your health status. Regular tests may be needed if you have chronic conditions like kidney disease or liver problems.
Can diet affect my protein test results?
Yes, diet can influence protein levels. High-protein diets or malnutrition may lower levels, while dehydration can raise them. Follow your doctor’s advice on dietary adjustments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy