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Fetal hemoglobin (HbF) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fetal hemoglobin, a type of hemoglobin found in newborns and some adults with certain blood conditions.

Quick summary

["Fetal hemoglobin helps diagnose or monitor conditions like thalassemia or sickle cell disease in adults or newborns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37060-1
Short code
XR Fetal Views
Synonyms
XR Fetal Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order this test to check for fetal hemoglobin levels in adults with blood disorders, such as thalassemia or sickle cell trait. It can also be part of newborn screening or research studies involving fetal hemoglobin.

What does the test involve?

A blood sample is taken from a vein in your arm. The blood is then processed to measure the concentration of fetal hemoglobin in the serum or plasma.

What should you expect before the test?

No special preparation is usually needed, but you may be asked to fast for a few hours if instructed by your provider. Wear comfortable clothing and plan to stay near the testing site for a short time.

What are the possible results?

Results will be provided as a concentration value of fetal hemoglobin. Your healthcare provider will interpret these results in the context of your medical history and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbF (Serum/Plasma)

Frequently asked questions

What does a high fetal hemoglobin level mean?
A high fetal hemoglobin level may suggest conditions such as beta-thalassemia or sickle cell trait, which can affect how your blood carries oxygen. It can also be seen in newborns or during certain treatments.
How is fetal hemoglobin tested?
The test uses a blood sample processed to measure fetal hemoglobin concentration through specialized laboratory methods, often involving immunoassay techniques.
Is there any risk or discomfort with this test?
There is usually minimal discomfort during the blood draw, which may include a slight sting. Rarely, there could be bruising or slight swelling at the site. Most people feel fine afterward.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy