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Serum/Plasma Sodium Concentration (Hyponatremia/Sodium Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sodium in your blood, which helps your body maintain proper fluid balance and nerve function.

Quick summary

["Sodium levels help doctors check if you’re retaining or losing too much fluid or salt."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37604-6
Short code
XR Nasal bones 3V
Synonyms
XR Nasal bones 3V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Sodium is a key mineral that helps regulate how fluids move in and out of your cells. Too little sodium (hyponatremia) can cause headaches, confusion, or even seizures, while too much (hypernatremia) may lead to dehydration symptoms like extreme thirst or muscle spasms. Your doctor may order this test to diagnose conditions like kidney problems, heart failure, or excessive sweating.

When You Might Need It

You may need this test if you have symptoms like confusion, swelling, rapid heartbeat, or unexplained weight gain. Doctors also check sodium levels before surgeries, during chemotherapy, or if you’re taking certain medications (like diuretics) that affect fluid balance.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is sent to a lab where it’s separated into serum or plasma for testing. Sodium levels are measured using an automated method that detects the mineral’s concentration in your blood.

What to Expect Before the Test

No special preparation is needed, but avoid drinking extra water or salt 24 hours before if your doctor directs you to. If you’re on certain medications (like diuretics), let your doctor know—it may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Sodium Level

Frequently asked questions

How does sodium imbalance affect my health?
Low sodium (hyponatremia) can cause neurological issues like headaches, dizziness, or even seizures. High sodium (hypernatremia) may lead to dehydration, muscle cramps, or confusion. Your doctor will use this test alongside symptoms and other tests to diagnose the cause, such as kidney problems, heart disease, or hormonal imbalances.
What causes sodium levels to change?
Sodium levels can drop from excessive vomiting, diarrhea, sweating, or certain medications (like diuretics or antipsychotics). They may rise from dehydration, kidney disease, or high salt intake. Lifestyle factors like diet and activity level also play a role.
Can I adjust my sodium intake based on this test?
Not without consulting your doctor. Sodium levels are influenced by many factors, including medications, kidney function, and overall health. Your doctor will guide you on diet or lifestyle changes if needed, but sudden changes can be dangerous.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy