Serum Creatinine (Creatinine Level)
This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.
["A creatinine test checks kidney function by measuring waste in your blood."]
Key facts at a glance
- LOINC
- 103397-6
- Short code
- XR Neck 1V
- Synonyms
- XR Neck 1V
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 22
- Ref high
- 198
- Critical range
- — – 10000 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xr
- CPT
- 82553
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. High levels can indicate kidney problems, while low levels may suggest dehydration or muscle loss. This test is often used alongside other measures to evaluate kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If you’re on a low-protein diet or have recently exercised, let your healthcare provider know, as these factors can slightly affect results.
What the Results Mean
Results are compared to a reference range, which can vary slightly by lab. Higher-than-normal levels may signal kidney issues, while very low levels could point to conditions like severe dehydration or muscle wasting. Your doctor will interpret results in the context of your overall health.
Common Causes of Abnormal Results
High creatinine levels may be caused by kidney disease, dehydration, severe muscle injury, or conditions that reduce blood flow to the kidneys. Low levels might result from dehydration, low muscle mass, or certain medications. Other factors, like pregnancy or liver disease, can also influence results.
Reference range
Adult males: 22-198 U/L; Females: 22-198 U/LN/A
No special preparation required. Inform provider of any chest pain or symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Creatinine
Frequently asked questions
Is creatinine testing part of a routine checkup?
Can diet affect creatinine levels?
What if my creatinine level is high?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy