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C-reactive protein (CRP) concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of C-reactive protein in your blood, a protein produced by your liver in response to inflammation.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
103473-5
Short code
XR Neck 2V
Synonyms
XR Neck 2V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CRP test to check for signs of inflammation in your body. This could be due to infections (like pneumonia or urinary tract infections), injuries, or conditions like arthritis or heart disease. It may also be used to monitor how well treatments for these conditions are working.

What Does a High or Low CRP Level Mean?

A higher than normal CRP level often indicates inflammation. Very high levels may suggest severe infections or other serious conditions. A low level usually means there is little to no inflammation, but this can vary depending on your overall health and medical history.

How Is the CRP Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure CRP levels using an immunoassay method.

What Are Common Causes of Abnormal CRP Levels?

CRP levels can be elevated due to infections, injuries, surgeries, or certain medical conditions like rheumatoid arthritis, lupus, or heart disease. It can also be affected by factors like smoking, stress, or certain medications.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP plays a key role in identifying and monitoring inflammation-related health issues. It can help doctors diagnose conditions early, guide treatment plans, and track progress over time. However, CRP alone is not diagnostic for specific diseases and should be interpreted alongside other test results and clinical findings.

Short name

CRP

Frequently asked questions

What does a CRP test measure?
A CRP test measures the concentration of C-reactive protein in your blood, which is produced by your liver in response to inflammation.
Can CRP levels change with diet or lifestyle?
Yes, lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. For example, a healthy diet and regular exercise may help lower CRP levels, while smoking or poor diet can increase them.
How soon after a procedure or injury should I expect CRP levels to change?
CRP levels can rise within days after an infection, injury, or surgery. The exact timing depends on the cause, but they often return to normal within a few weeks. Your doctor will interpret the results in the context of your specific situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy