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Serum or plasma substance concentration (qualitative) for a renal marker (e.g., protein or metabolite)

Published: August 9, 2026Updated: August 17, 2026

This test checks for the presence of certain substances in your blood that may indicate kidney function or potential kidney-related issues, such as protein loss or metabolic byproducts.

Quick summary

["Helps identify early kidney problems or abnormalities in blood chemistry that may require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
42441-6
Short code
XR Neck Mag
Synonyms
XR Neck Mag
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific substances in your blood that could signal kidney function concerns. While the exact substance isn’t specified, it may include proteins, small molecules, or metabolites that are processed by the kidneys. Some examples could involve proteinuria (protein in urine-like substances) or abnormal metabolites that accumulate when kidneys aren’t working properly.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like swelling, fatigue, changes in urine appearance, or if they suspect kidney disease, chronic illness, or exposure to toxins that could affect kidney function.

Common Reasons for Testing

Tests like this are often used in routine check-ups for patients with risk factors (e.g., diabetes, hypertension), during monitoring of chronic conditions, or after exposure to substances that may harm kidneys.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma for testing. This process is quick and usually done in a lab setting.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal results may indicate kidney dysfunction, metabolic disorders, or other systemic conditions. While qualitative tests don’t provide exact measurements, they can flag areas for further investigation, such as additional lab tests, imaging, or medical evaluation to determine the cause and guide treatment.

Short name

Qualitative renal protein/metabolite screen

Frequently asked questions

What does a positive or abnormal result mean?
A positive or abnormal result suggests that your body may be producing or retaining substances at levels that could indicate kidney issues or other health concerns. This doesn’t always mean you have a problem, but it will prompt your doctor to investigate further with more tests or discussions about your health.
How long will I need to prepare for this test?
No special preparation is usually needed. You may be asked to fast for a few hours before the test if it involves a specific type of blood sample, but this is not always the case for qualitative tests. Follow your healthcare provider’s instructions.
Can I take any medications before this test?
Some medications may affect test results, but this test is generally not affected by common medications. Always inform your healthcare provider about all medications, supplements, or herbal products you’re taking before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy