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Optic Foramen Protein Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures various proteins and substances in your blood that may relate to conditions affecting the optic nerve or surrounding structures, such as inflammation, infection, or metabolic disorders.

Quick summary

["Understanding your protein levels can help identify potential health concerns affecting vision or nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37609-5
Short code
XR Optic foramen 4V
Synonyms
XR Optic foramen 4V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The optic foramen is a small opening in the skull where the optic nerve exits. This test evaluates proteins and biomarkers in serum or plasma that could indicate issues like optic neuritis, inflammation, or other systemic conditions. Specific analytes may include markers for immune response, nerve damage, or metabolic processes.

Common Uses

This test may be used to diagnose or monitor conditions such as optic neuritis, multiple sclerosis, or other neurological or inflammatory diseases that impact vision. It can also help assess metabolic disorders or infections affecting the optic nerve.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma, which is then analyzed. This test requires fasting or specific dietary restrictions depending on the analytes measured.

Preparation and Timing

Follow your healthcare provider’s instructions regarding fasting or timing of the test. Some proteins may be affected by recent meals or hydration levels, so preparation is critical for accurate results.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated or altered levels of certain proteins in this test can signal inflammation, nerve damage, infections, or metabolic imbalances. For example, increased inflammatory markers may indicate optic neuritis or autoimmune conditions. Low or abnormal levels could suggest deficiencies or other underlying health issues. Always discuss results with your doctor to interpret their meaning in your specific situation.

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like sudden vision changes, pain around your eyes, or signs of neurological conditions. It could also be part of a broader evaluation for autoimmune diseases, infections, or metabolic disorders.
What do the results mean?
Results can vary widely based on the specific proteins measured. Your doctor will compare your results to your health history and symptoms to determine if further testing or treatment is needed. Some results may be normal, while others could point to areas for further investigation.
Are there any risks or side effects?
Blood draws are generally safe, but you may experience mild discomfort or bruising at the site. Rarely, there could be allergic reactions to the process or minor bleeding. Always inform your healthcare provider about any allergies or conditions before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy