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Vitamin D Binding Protein (DBP) Total Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of Vitamin D Binding Protein in your blood. It helps assess how well your body transports and regulates vitamin D.

Quick summary

["Vitamin D Binding Protein supports vitamin D metabolism and transport in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36886-0
Short code
XR Orbit Views
Synonyms
XR Orbit Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if they suspect conditions affecting vitamin D metabolism, such as kidney disease, liver disease, or certain genetic disorders. It can also be part of a broader evaluation for vitamin D deficiency or related disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Bring any medications or supplements you’re taking to your appointment.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The process is quick and typically causes only minor discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are used to evaluate how your body processes and transports vitamin D. Abnormal levels may indicate conditions affecting protein function or vitamin D balance, but interpretation depends on clinical context and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D Binding Protein plays a key role in transporting vitamin D in the blood. Low levels may suggest conditions like nephrotic syndrome, liver disease, or genetic disorders affecting protein synthesis. High levels could be seen in certain genetic variants or metabolic conditions. Always discuss results with your provider for personalized interpretation.

Short name

Total Vitamin D Binding Protein

Frequently asked questions

What does a high or low Vitamin D Binding Protein level indicate?
High levels may be associated with certain genetic variants or conditions like nephrotic syndrome, where the kidneys lose protein into urine. Low levels could indicate liver disease, kidney dysfunction, or other metabolic issues affecting protein production or transport. Your provider will consider your full medical history and other test results to determine significance.
How often should I get this test?
The frequency depends on your health status. If you have a known condition affecting vitamin D metabolism or protein function, your provider may recommend regular monitoring. Otherwise, this test is often part of a broader evaluation and may not be routine unless symptoms or risk factors suggest it.
Can diet or supplements affect Vitamin D Binding Protein levels?
While Vitamin D Binding Protein itself is not directly influenced by diet or supplements, conditions like kidney or liver disease—commonly influenced by diet—can alter its levels. Always follow your provider’s advice regarding dietary changes or supplements, especially if you’re taking medications that interact with protein metabolism.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy