Serum or Plasma Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormalities in protein distribution, which may indicate conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors check for unusual protein patterns that could signal hidden health issues."]
Key facts at a glance
- LOINC
- 41773-3
- Short code
- XR port Face Views
- Synonyms
- XR port Face Views
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xr-portable
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if they suspect conditions like multiple myeloma (a cancer of plasma cells), chronic liver disease, kidney disease, or certain types of autoimmune disorders. It’s also used to monitor treatment progress or screen for genetic disorders affecting protein production.
What Does the Test Involve?
A blood sample is taken from a vein in your arm. The blood is then separated into its components, including proteins. A gel or paper strip is applied to the sample, and an electric current is passed through it. Proteins move at different speeds depending on their structure, creating bands that represent various protein types.
Sample Collection and Preparation
The test uses either serum (liquid part of blood after clotting) or plasma (liquid part of blood without clotting). No special preparation is needed, but fasting may be advised depending on your provider’s instructions.
What Are Common Findings?
Normal results show distinct bands corresponding to albumin, alpha, beta, and gamma globulins. Abnormal findings might include extra bands (e.g., Bence Jones proteins in multiple myeloma), reduced albumin, or increased globulins, which can signal underlying health concerns.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein electrophoresis can reveal hidden conditions such as multiple myeloma (where abnormal proteins like Bence Jones proteins appear), liver or kidney disease (altered albumin and globulin levels), or inflammatory or autoimmune disorders (elevated acute-phase proteins). It’s also used to monitor treatment responses in patients with these conditions.
Short name
Protein Electrophoresis
Frequently asked questions
How long does it take to get results?
What does it mean if my results are abnormal?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy