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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function and overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36328-3
Short code
XR Ribs-Bl 4V
Synonyms
XR Ribs-Bl 4V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a history of kidney problems. It can also be used to check for kidney disease, track kidney function over time, or evaluate the effects of certain medications or treatments on your kidneys.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader kidney function panel. Drink plenty of water the day before if your doctor recommends it, as hydration can help prepare your kidneys for testing.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. The blood sample is sent to a lab for analysis. The test typically takes a few minutes, and you may feel slight discomfort or bruising at the injection site.

What the Results Mean

Higher than expected creatinine levels may suggest kidney problems, while lower levels could indicate dehydration or muscle breakdown. Your doctor will interpret results in relation to your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Elevated levels often signal impaired kidney function, which can lead to buildup of waste products in your blood. Regular monitoring helps detect kidney issues early and guides treatment decisions.

Short name

Creatinine

Frequently asked questions

What causes creatinine levels to be higher than usual?
Several factors can affect creatinine levels, including dehydration, muscle mass, certain medications, or kidney disease. If your levels are elevated, your doctor may recommend further tests or adjustments to your treatment plan.
Is fasting required for this test?
Not always. Some labs may ask for fasting if this test is part of a broader panel, but others do not require it. Always follow your doctor’s specific instructions for your test.
How often should I get this test?
Frequency depends on your health. People with kidney disease may need tests more often, while others with stable conditions may only need it periodically. Your doctor will determine the best schedule for you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy