Skip to content

Serum or Plasma Substance Concentration (Bromocresol Green) Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in your blood using a dye called bromocresol green. It helps assess how proteins like albumin and globulins are separated in your serum or plasma.

Quick summary

["This test helps diagnose conditions affecting protein balance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26151-1
Short code
XR Ribs-Bl Views
Synonyms
XR Ribs-Bl Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Bromocresol Green Electrophoresis Used For?

Electrophoresis with bromocresol green is primarily used to evaluate protein patterns in the blood. It can help identify abnormalities in protein fractions, such as those seen in conditions like multiple myeloma, liver disease, or certain autoimmune disorders.

How Is the Test Performed?

A small blood sample is drawn, usually from your arm. The serum or plasma is then separated and mixed with bromocresol green dye. An electric current is applied to the sample, causing proteins to move based on their size and charge. The distribution of proteins is then analyzed to determine their relative concentrations.

What Conditions Might Require This Test?

This test may be ordered if you have symptoms or conditions that could affect protein levels, such as unexplained weight loss, fatigue, swollen lymph nodes, or signs of liver or kidney disease. It can also be part of routine monitoring for certain chronic conditions.

Preparation for the Test

No special preparation is typically required. You may be asked to fast for a few hours before the test if instructed by your healthcare provider, but this is not always the case for electrophoresis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Bromocresol green electrophoresis can reveal imbalances in protein fractions, which may indicate underlying health issues. For example, an abnormal protein pattern could suggest conditions like monoclonal gammopathy (seen in multiple myeloma), liver disease, or inflammatory disorders. Early detection can guide treatment decisions and monitor disease progression.

Short name

BCG Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test to investigate symptoms like unexplained weight changes, fatigue, or signs of protein-related disorders. It can also be part of a broader evaluation for conditions affecting the liver, kidneys, or immune system.
What does the test result mean?
Results show the distribution of proteins in your blood. Abnormal patterns may indicate conditions like protein abnormalities, liver disease, or other metabolic issues. Your healthcare provider will interpret the results in the context of your symptoms and medical history.
Is there any risk or discomfort with this test?
The test involves a small blood draw, which may cause mild discomfort or bruising at the site. There are no significant risks associated with the electrophoresis process itself, but always follow your healthcare provider’s instructions for any post-test care.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy