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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps evaluate kidney function and detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42313-7
Short code
XR Ribs-L 1V
Synonyms
XR Ribs-L 1V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste products, including creatinine, from your blood. High levels can indicate poor kidney function or damage, while low levels may suggest overhydration or other conditions. This test is often used alongside other measures, like blood urea nitrogen (BUN), to assess kidney health.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before testing if your doctor specifies it. Avoid excessive alcohol or certain medications that could affect results. Hydration levels may also be considered if your doctor requests it.

Common Causes of Abnormal Results

High creatinine levels may signal kidney disease, dehydration, or conditions like heart failure or muscle disorders. Low levels might suggest dehydration, overhydration, or certain liver or muscle conditions. Always discuss symptoms or recent changes with your healthcare provider.

How Results Are Used in Care

Doctors use creatinine levels to monitor kidney function over time, guide treatment plans, and detect early kidney problems. It’s often part of a broader panel that includes other blood or urine tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing and managing kidney disease, monitoring chronic conditions like diabetes or hypertension, and ensuring proper treatment adjustments. It helps prevent complications by identifying issues early.

Short name

Creatinine Level

Frequently asked questions

What triggers a creatinine test?
A creatinine test may be ordered if you have symptoms like swelling, fatigue, or changes in urine output; if you have a history of kidney disease, diabetes, or high blood pressure; or if your doctor wants to monitor a chronic condition.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss them with you during your follow-up visit.
Can diet or exercise affect creatinine levels?
Dietary protein intake can influence creatinine levels, but moderate changes are usually well-tolerated. High protein diets may temporarily raise levels, while very low protein diets may lower them. Always follow your doctor’s advice regarding diet and activity.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy