Serum or plasma concentration of ribonucleic acid (RNA) by high-performance liquid chromatography (HPLC)
This test measures the amount of RNA, a key molecule involved in protein synthesis, in your blood. It may be used to assess certain genetic or metabolic conditions.
["RNA levels can help diagnose or monitor conditions affecting RNA metabolism."]
Key facts at a glance
- LOINC
- 37964-4
- Short code
- XR Ribs post-R Views
- Synonyms
- XR Ribs post-R Views
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xr
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms or risk factors related to RNA-related disorders, such as genetic mutations affecting RNA processing or inherited metabolic diseases. It could also be part of a broader evaluation for unexplained liver, kidney, or muscle issues.
What Does the Test Involve?
A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is analyzed using HPLC to measure RNA concentration. This process is generally safe and well-tolerated, with possible minor discomfort at the needle insertion site.
What Are Possible Results?
Results are expressed as a concentration value (e.g., micrograms per milliliter or milligrams per deciliter) but specific reference ranges are not universally standardized. Your results will be compared to your individual baseline or clinical context.
What Does It Mean If My Results Are Abnormal?
Abnormal RNA levels may suggest underlying conditions like certain genetic disorders, infections, or metabolic syndromes. Elevated or low levels could indicate issues with RNA synthesis, degradation, or transport within your cells.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
RNA testing can play a critical role in diagnosing genetic disorders, such as those affecting RNA splicing or stability, and monitoring conditions like liver disease or certain cancers where RNA profiles can provide insights into disease progression. It may also help evaluate responses to treatments targeting RNA pathways.
Short name
RNA Level (Serum/Plasma)
Frequently asked questions
What causes RNA levels to change?
How often should I get this test?
Can lifestyle changes affect RNA levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy