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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, which can help assess liver function or protein synthesis.

Quick summary

["A dye-binding test to evaluate liver health or protein levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37938-8
Short code
XR Ribs post Views
Synonyms
XR Ribs post Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Bromocresol green (BCG) is a dye that binds specifically to albumin, a key protein in your blood. When this dye binds to albumin, it changes color. The test measures how much dye binds, which reflects your blood’s albumin levels. Lower albumin levels may indicate liver disease, malnutrition, or other conditions affecting protein production.

Why Your Doctor Might Order This Test

Doctors may use this test to check for liver problems, such as cirrhosis or hepatitis, or to monitor conditions like kidney disease or malnutrition. It can also help assess how well your body is retaining proteins after surgery or treatment.

Common Uses and Conditions Monitored

This test is less commonly used today compared to newer methods but may still be part of broader liver function or protein evaluation. It’s sometimes used in research or older diagnostic protocols.

What to Expect Before the Test

No special preparation is needed, but you may fast for 8–12 hours before the blood draw if instructed. Bring your lab results or medical history to your appointment for clarity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Dye Binding Assay

Frequently asked questions

How does this test differ from other liver function tests like ALT or bilirubin?
This test specifically measures albumin binding capacity, which is distinct from enzymes like ALT or bilirubin. Albumin levels can be affected by liver disease, kidney issues, or protein loss, while ALT measures liver cell damage. Your doctor will interpret results in context with other tests.
What are the typical reference ranges for this test?
Reference ranges vary by lab and method, but albumin binding capacity is often reported as a qualitative or semi-quantitative result rather than a fixed numeric value. Your results will be compared to your baseline or clinical context.
Can this test detect early liver disease?
While this test can indicate protein-related liver issues, it’s not as sensitive as newer imaging or biomarker tests for early detection. Your doctor may combine results with other tests for a full assessment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy