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Serum or Plasma Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle breakdown, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26153-7
Short code
XR Ribs-R Views
Synonyms
XR Ribs-R Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels can indicate how well your kidneys are working. High levels may suggest kidney problems, while low levels could indicate dehydration or muscle loss. This test is often used alongside other kidney function tests to diagnose or monitor conditions like chronic kidney disease.

What to Expect Before the Test

You may be asked to fast before this test, but it’s not always required. Drink plenty of water the day before if you’re dehydrated. Avoid heavy exercise or certain medications that could affect results. Your blood will be drawn from a vein, usually in your arm.

What the Results Mean

Results are compared to a general reference range, but individual ranges can vary by lab. High creatinine levels may signal kidney issues, while very low levels might need further investigation. Your doctor will discuss results in the context of your overall health.

Common Causes of Abnormal Results

High creatinine levels can result from kidney disease, dehydration, or conditions that reduce blood flow to the kidneys. Low levels may occur with muscle wasting, severe dehydration, or certain medications. Other factors like age, sex, and muscle mass can also influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

How often do I need this test?
Your doctor may order this test regularly if you have kidney problems, diabetes, or high blood pressure. Others may need it less often, depending on your health. Follow your healthcare provider’s recommendations for follow-up testing.
Can I eat or drink before this test?
Some labs may ask for fasting, but others do not. Always check with your lab or doctor before the test. If you’re unsure, ask your healthcare provider for guidance.
What if my results are outside the normal range?
If your results are abnormal, your doctor will review them with you and may recommend further tests or adjustments to your treatment plan. They’ll also discuss lifestyle or medication changes if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy