Serum or Plasma Protein Electrophoresis (Qualitative) – Bromocresol Purple Method

What This Test Measures

Protein electrophoresis separates blood proteins into fractions (e.g., albumin, globulins) using an electric field. The bromocresol purple dye binds to proteins, creating visible bands that indicate protein concentration levels in each fraction. This qualitative method helps detect imbalances that may not be seen in standard protein tests.

Why It’s Done

Your doctor may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or abnormal lab results. It’s also used to monitor conditions like multiple myeloma, liver disease, or kidney disorders that affect protein production or breakdown.

Sample Collection

A blood sample is drawn from a vein, usually in your arm. The blood is then separated into plasma or serum for testing. This test does not require fasting.

Common Conditions Monitored

Abnormal protein patterns can signal conditions such as multiple myeloma (cancer of plasma cells), Waldenström macroglobulinemia, liver cirrhosis, or kidney disease. It may also help diagnose inflammatory diseases or detect hidden protein abnormalities.