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Serum Calcium Concentration (with 24-Hour Collection Qualifier)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of calcium in your blood serum over a 24-hour period. Calcium is an essential mineral that helps with muscle and nerve function, bone health, and blood clotting.

Quick summary

["Understanding your 24-hour calcium levels helps doctors assess long-term mineral balance and identify potential deficiencies or excesses over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79367-9
Short code
XR Sacrum+Coccyx GE 2V
Synonyms
XR Sacrum+Coccyx GE 2V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
CPT
82670
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, bone pain, or unusual fatigue. It could also be used to monitor conditions such as kidney disease, vitamin D deficiency, or metabolic bone disorders. Rarely, it may be part of a broader evaluation for unexplained calcium imbalances or chronic conditions like hyperparathyroidism.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw at a clinic or lab, and the serum portion will be collected for analysis. If you’re taking calcium supplements or certain medications, let your provider know, as they may affect results.

What the Results Mean

Calcium levels in blood can fluctuate based on diet, hydration, and health status. A 24-hour collection helps provide a more accurate picture of your body’s calcium handling. Results are typically reported as a concentration value, but your doctor will interpret them in the context of your overall health.

Common Causes of Abnormal Results

Low calcium levels (hypocalcemia) can occur due to vitamin D deficiency, kidney problems, or certain medications. High calcium levels (hypercalcemia) may result from overactive thyroid, bone diseases, or prolonged vitamin A exposure. Both extremes can cause serious health issues if untreated.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Calcium (24h)

Frequently asked questions

How long does it take to get my test results back?
Results are usually available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will contact you directly with the findings once they are ready.
Can I eat or drink anything before this test?
Yes, you can eat and drink normally before this test. Since it’s a blood draw, fasting is not required. However, if you’re taking calcium supplements or have specific dietary restrictions, inform your provider beforehand.
What if my calcium levels are out of the normal range?
If your results are abnormal, your doctor will discuss potential causes and next steps, which may include further testing, dietary adjustments, or treatment. Follow-up may involve monitoring calcium levels over time or addressing underlying conditions like kidney disease or vitamin deficiencies.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy