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Serum Calcium (Substance Concentration) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of calcium present in your blood serum. Calcium is an essential mineral that plays a key role in muscle function, nerve signaling, and bone health.

Quick summary

["Your blood calcium levels help ensure proper bone strength and normal bodily functions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69264-0
Short code
XR Sacrum Views W Stand
Synonyms
XR Sacrum Views W Stand
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to help your doctor check how well your body is working, look for signs of illness, and guide decisions about your ongoing care and treatment.

Your healthcare provider may order this test to check for conditions affecting calcium balance, such as low or high calcium levels (hypocalcemia or hypercalcemia), kidney disease, bone disorders, or metabolic issues like hyperparathyroidism. It may also be part of routine screening or monitoring for certain medical conditions.

Before the test, your care team will explain the steps and tell you how to prepare, which may include avoiding certain foods, drinks, or medicines for a short time.

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic evaluation. Bring any medications you’re currently taking, as some (like calcium supplements or certain diuretics) can affect results.

During the test, a trained member of your care team will perform the procedure in a comfortable setting, explain each step as it happens, and answer any questions you have.

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.

Possible results may show that everything looks normal, or they may point to a condition that needs closer attention, further testing, or treatment, which your doctor will explain.

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). While reference ranges vary by lab, low or high values may signal underlying health concerns that need further investigation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Calcium

Frequently asked questions

Low calcium levels (hypocalcemia) can cause muscle cramps, numbness, irregular heartbeat, or fatigue. High calcium levels (hypercalcemia) may lead to nausea, confusion, kidney stones, or weak bones. Both conditions require medical attention to prevent complications.
How long will it usually take before my test results are ready and shared with me by my doctor or another member of my healthcare team?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss them with you during your follow-up visit.
Can I eat or drink anything before this test, or will I need to avoid food, drinks, or certain medicines for a set amount of time ahead of the appointment?
If fasting is required (e.g., for metabolic testing), avoid food and liquids—except water—8–12 hours before drawing blood. If no fasting is needed, you can eat and drink normally.
You may experience mild bruising or soreness at the injection site, which usually fades within a day. Apply ice if needed. Avoid heavy lifting or strenuous activity for 24 hours to prevent excessive bleeding.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy