Serum or Plasma Creatinine Concentration (Standard Method)
This test measures the level of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.
["A creatinine test helps evaluate kidney function and detect early kidney damage."]
Key facts at a glance
- LOINC
- 37867-9
- Short code
- XR Skull 2V
- Synonyms
- XR Skull 2V
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xr
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Your kidneys normally filter waste products, including creatinine, from your blood. High levels of creatinine can signal impaired kidney function, while low levels may indicate dehydration or other conditions. This test is often used alongside other measures to monitor kidney health, especially in people with risk factors like diabetes, high blood pressure, or a family history of kidney disease.
What to Expect Before the Test
You may be asked to fast for a few hours before the test, but this is not always required. Drink plenty of water the day before if you suspect dehydration. Avoid strenuous exercise or certain medications that could affect kidney function, but always follow your healthcare provider’s specific instructions.
During the Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch or discomfort, but it usually takes only a few minutes. If you’re concerned about needles, let your provider know so they can offer alternatives.
What the Results Mean
Results are compared to a reference range, which can vary slightly by lab. High creatinine levels may indicate kidney problems, while very low levels might suggest dehydration or other conditions. Your doctor will interpret results in the context of your overall health and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Creatinine
Frequently asked questions
How often should I get this test?
Can diet or hydration affect creatinine levels?
What if my results are outside the normal range?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy