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Serum or plasma mass concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and bile flow.

Quick summary

["Your liver’s ability to process bilirubin can signal liver health or potential issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30889-0
Short code
XR TMJ-L Views
Synonyms
XR TMJ-L Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is normally processed by your liver and excreted through bile into your intestines. If your liver isn’t working well, bilirubin can build up in your blood, leading to jaundice (yellowing of skin/eyes). This test helps detect early signs of liver disease, bile duct blockages, or hemolytic anemia (red blood cell destruction).

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm. If you’re on a blood thinner, let your provider know to avoid unnecessary bleeding.

Common Causes of Elevated or Low Levels

High bilirubin levels may occur with liver diseases (e.g., hepatitis), gallbladder issues, or hemolytic anemia. Low levels are less common but can happen with liver damage or certain medications.

How Results Are Interpreted

Results are compared to a reference range (not provided here). High levels often trigger further liver tests, while low levels may require investigation into underlying causes like malnutrition or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

Could my bilirubin levels be normal even if I feel unwell?
Normal levels don’t always mean everything is fine. If you have symptoms like fatigue, dark urine, or pale stools, discuss results with your provider—even if they’re within range, other factors may be at play.
Why does my doctor order this test?
Your doctor may request it to check for liver problems, diagnose jaundice, or monitor conditions like hepatitis, cirrhosis, or red blood cell disorders. It’s also used in newborns to screen for bilirubin-related jaundice.
What if my results are outside the usual range?
Follow your doctor’s instructions for next steps. They may recommend additional tests (e.g., liver function panels) or lifestyle changes to address potential causes, such as diet or medication adjustments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy