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Serum or Plasma Total Protein with Electrophoresis Profile (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood, often used to check for conditions affecting protein balance, such as kidney disease or liver problems.

Quick summary

["Helps identify protein abnormalities that may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25013-4
Short code
XR Toes Views
Synonyms
XR Toes Views
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins into different fractions (e.g., albumin, globulins) based on size and charge. This qualitative test does not provide exact quantities but helps detect shifts in protein distribution.

Common Uses in Diagnosis

Used to diagnose conditions like multiple myeloma, nephrotic syndrome, or chronic liver disease, where protein patterns differ from normal.

Sample Preparation Notes

A blood sample is drawn, typically collected in a plain tube (no additives). Proteins are separated using an electric field in a gel medium, with results interpreted visually or via densitometry.

When This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if routine blood tests show abnormal protein levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein Electrophoresis (Qualitative)

Frequently asked questions

Why might my doctor want to check my protein levels?
To evaluate conditions affecting protein synthesis, breakdown, or transport (e.g., kidney disease, liver dysfunction, or immune disorders). Abnormal patterns may indicate hidden issues like protein-losing syndromes or monoclonal gammopathies.
What do the different protein bands mean?
Each band represents a group of proteins. For example, a high globulin band might suggest inflammation or immune system issues, while unusual spikes could indicate conditions like multiple myeloma.
How long does it take to get results?
Results are typically available within 24–48 hours, depending on lab processing. Follow-up with your doctor to discuss findings and next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy